Emotional Dysregulation in Adolescents: Implications for the Development of Severe Psychiatric Disorders, Substance Abuse, and Suicidal Ideation and Behaviors

Well-tuned emotional regulation is fundamental for human life and psychological well-being.Negative physiological emotions are counterbalanced by positive ones, and this equilibrium is the mainstay of human physiological affective states.However, this mechanism may sometimes become dysfunctional when negative emotions are not correctly counterbalan

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Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

Abstract Background Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite survival.The recruitment of alternatively activated macrophages (AAMs) has been observed in a variety of helminth inf

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